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(2R,3S,2”R,3”R)-manniflavanone, a new gastrointestinal smooth muscle L-type calcium channel inhibitor, which underlies the spasmolytic properties of Garcinia buchananii stem bark extract
Garcinia buchananii Baker stem bark extract (GBB) is a traditional medication of diarrhea and dysentery in sub-Saharan Africa. It is believed that GBB causes gastrointestinal smooth muscle relaxation. The aim of this study was to determine whether GBB has spasmolytic actions and identify compounds u...
Autores principales: | Balemba, Onesmo B., Stark, Timo D., Lösch, Sofie, Patterson, Savannah, McMillan, John S., Mawe, Gary M., Hofmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japan Society of Smooth Muscle Research
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826780/ https://www.ncbi.nlm.nih.gov/pubmed/26081368 http://dx.doi.org/10.1540/jsmr.50.48 |
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