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Genetic Architecture of MAPT Gene Region in Parkinson Disease Subtypes

The microtubule-associated protein tau (MAPT) region has been conceptualized as a model of the interaction between genetics and functional disease outcomes in neurodegenerative disorders, such as Parkinson disease (PD). Indeed, haplotype-specific differences in expression and alternative splicing of...

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Detalles Bibliográficos
Autores principales: Pascale, Esterina, Di Battista, Maria Elena, Rubino, Alfonso, Purcaro, Carlo, Valente, Marcella, Fattapposta, Francesco, Ferraguti, Giampiero, Meco, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826864/
https://www.ncbi.nlm.nih.gov/pubmed/27147968
http://dx.doi.org/10.3389/fncel.2016.00096