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Real Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand Breaks

Ubiquitin and the ubiquitin-like modifier SUMO are intimately connected with the cellular response to various types of DNA damage. A striking feature is the local accumulation of these proteinaceous post-translational modifications in the direct vicinity to DNA double-strand breaks, which plays a cr...

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Detalles Bibliográficos
Autores principales: Dantuma, Nico P., Pfeiffer, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826866/
https://www.ncbi.nlm.nih.gov/pubmed/27148355
http://dx.doi.org/10.3389/fgene.2016.00058