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Subtractive Cell-SELEX Selection of DNA Aptamers Binding Specifically and Selectively to Hepatocellular Carcinoma Cells with High Metastatic Potential

Relapse and metastasis are two key risk factors of hepatocellular carcinoma (HCC) prognosis; thus, it is emergent to develop an early and accurate detection method for prognostic evaluation of HCC after surgery. In this study, we sought to acquire oligonucleotide DNA aptamers that specifically bind...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Yuan, Chun-Hui, Yang, Yi-Fei, Yin, Chang-Qing, Guan, Qing, Wang, Fu-Bing, Tu, Jian-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826907/
https://www.ncbi.nlm.nih.gov/pubmed/27119081
http://dx.doi.org/10.1155/2016/5735869