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Positive Selection and Centrality in the Yeast and Fly Protein-Protein Interaction Networks

Proteins within a molecular network are expected to be subject to different selective pressures depending on their relative hierarchical positions. However, it is not obvious what genes within a network should be more likely to evolve under positive selection. On one hand, only mutations at genes wi...

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Detalles Bibliográficos
Autores principales: Chakraborty, Sandip, Alvarez-Ponce, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826914/
https://www.ncbi.nlm.nih.gov/pubmed/27119079
http://dx.doi.org/10.1155/2016/4658506