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Characterization of sphere-forming HCT116 clones by whole RNA sequencing

PURPOSE: To determine CD133(+) cells defined as cancer stem cells (CSCs) in colon cancer, we examined whether CD133(+) clones in HCT116 demonstrate known features of CSCs like sphere-forming ability, chemodrug-resistance, and metastatic potential. METHODS: Magnetic cell isolation and cell separation...

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Detalles Bibliográficos
Autores principales: Chung, Eunkyung, Oh, Inkyung, Lee, Kil Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Surgical Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826980/
https://www.ncbi.nlm.nih.gov/pubmed/27073788
http://dx.doi.org/10.4174/astr.2016.90.4.183