Overexpression of a glucokinase point mutant in the treatment of diabetes mellitus

Glucokinase (GCK) is an important enzyme critical for glucose metabolism, and has been targeted as such in the pursuit of a cure for diabetes mellitus. We show that streptozotocin (STZ)-induced diabetic murine model exhibits low GCK expression with high blood glucose levels; moreover, aggravated glo...

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Detalles Bibliográficos
Autores principales: Lu, G, Teng, X, Zheng, Z, Zhang, R, Peng, L, Zheng, F, Liu, J, Huang, H, Xiong, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827006/
https://www.ncbi.nlm.nih.gov/pubmed/26752353
http://dx.doi.org/10.1038/gt.2016.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827006/
https://www.ncbi.nlm.nih.gov/pubmed/26752353
http://dx.doi.org/10.1038/gt.2016.1

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