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New Insights into the Generation of CD4 Memory May Shape Future Vaccine Strategies for Influenza

Influenza viral evolution presents a formidable challenge to vaccination due to the virus’ ability to rapidly mutate to evade immune responses. Live influenza infections generate large and diverse CD4 effector T cell responses that yield highly protective, long-lasting CD4 T cell memory that can tar...

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Detalles Bibliográficos
Autores principales: Devarajan, Priyadharshini, Bautista, Bianca, Vong, Allen M., McKinstry, Karl Kai, Strutt, Tara M., Swain, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827017/
https://www.ncbi.nlm.nih.gov/pubmed/27148257
http://dx.doi.org/10.3389/fimmu.2016.00136