Cargando…
New Insights into the Generation of CD4 Memory May Shape Future Vaccine Strategies for Influenza
Influenza viral evolution presents a formidable challenge to vaccination due to the virus’ ability to rapidly mutate to evade immune responses. Live influenza infections generate large and diverse CD4 effector T cell responses that yield highly protective, long-lasting CD4 T cell memory that can tar...
Autores principales: | Devarajan, Priyadharshini, Bautista, Bianca, Vong, Allen M., McKinstry, Karl Kai, Strutt, Tara M., Swain, Susan L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827017/ https://www.ncbi.nlm.nih.gov/pubmed/27148257 http://dx.doi.org/10.3389/fimmu.2016.00136 |
Ejemplares similares
-
Effector CD4 T cell transition to memory requires late cognate interactions that induce autocrine IL-2
por: McKinstry, K. Kai, et al.
Publicado: (2014) -
Expanding roles for CD4(+) T cells in immunity to viruses
por: Swain, Susan L., et al.
Publicado: (2012) -
Mouse Models Reveal Role of T-Cytotoxic and T-Reg Cells in Immune Response to Influenza: Implications for Vaccine Design
por: Sell, Stewart, et al.
Publicado: (2019) -
IL-15 supports the generation of protective lung-resident memory CD4 T cells
por: Strutt, Tara M., et al.
Publicado: (2017) -
Strong influenza-induced T(FH) generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection
por: Devarajan, Priyadharshini, et al.
Publicado: (2022)