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Histone H4 lysine 20 acetylation is associated with gene repression in human cells

Histone acetylation is generally associated with gene activation and chromatin decondensation. Recent mass spectrometry analysis has revealed that histone H4 lysine 20, a major methylation site, can also be acetylated. To understand the function of H4 lysine 20 acetylation (H4K20ac), we have develop...

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Detalles Bibliográficos
Autores principales: Kaimori, Jun-Ya, Maehara, Kazumitsu, Hayashi-Takanaka, Yoko, Harada, Akihito, Fukuda, Masafumi, Yamamoto, Satoko, Ichimaru, Naotsugu, Umehara, Takashi, Yokoyama, Shigeyuki, Matsuda, Ryo, Ikura, Tsuyoshi, Nagao, Koji, Obuse, Chikashi, Nozaki, Naohito, Takahara, Shiro, Takao, Toshifumi, Ohkawa, Yasuyuki, Kimura, Hiroshi, Isaka, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827026/
https://www.ncbi.nlm.nih.gov/pubmed/27064113
http://dx.doi.org/10.1038/srep24318