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Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth

PCP proteins maintain planar polarity in many epithelial tissues and have been implicated in cilia development in vertebrate embryos. In this study we examine Prickle3 (Pk3), a vertebrate homologue of Drosophila Prickle, in Xenopus gastrocoel roof plate (GRP). GRP is a tissue equivalent to the mouse...

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Detalles Bibliográficos
Autores principales: Chu, Chih-Wen, Ossipova, Olga, Ioannou, Andriani, Sokol, Sergei Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827067/
https://www.ncbi.nlm.nih.gov/pubmed/27062996
http://dx.doi.org/10.1038/srep24104