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IEX-1 deficiency induces browning of white adipose tissue and resists diet-induced obesity

Chronic inflammation plays a crucial role in the pathogenesis of obesity and insulin resistance. However, the primary mediators that affect energy homeostasis remain ill defined. Here, we report an unexpected role for immediate early response gene X-1 (IEX-1), a downstream target of NF-κB, in energy...

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Detalles Bibliográficos
Autores principales: Shahid, Mohd, Javed, Ammar A., Chandra, David, Ramsey, Haley E., Shah, Dilip, Khan, Mohammed F., Zhao, Liping, Wu, Mei X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827096/
https://www.ncbi.nlm.nih.gov/pubmed/27063893
http://dx.doi.org/10.1038/srep24135