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Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium

The small GTPase Rab5 has been well defined to control the vesicle-mediated plasma membrane protein transport to the endosomal compartment. However, its function in the internalization of vascular endothelial (VE)-cadherin, an important component of adherens junctions, and as a result regulating the...

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Detalles Bibliográficos
Autores principales: Yang, Junjun, Yao, Wei, Qian, Guisheng, Wei, Zhenghua, Wu, Guangyu, Wang, Guansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827161/
https://www.ncbi.nlm.nih.gov/pubmed/26112597
http://dx.doi.org/10.1007/s00018-015-1973-4