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The Akt signaling pathway is required for tissue maintenance and regeneration in planarians

BACKGROUND: Akt (PKB) is a serine threonine protein kinase downstream of the phosphoinositide 3-kinase (PI3K) pathway. In mammals, Akt is ubiquitously expressed and is associated with regulation of cellular proliferation, metabolism, cell growth and cell death. Akt has been widely studied for its ce...

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Detalles Bibliográficos
Autores principales: Peiris, T. Harshani, Ramirez, Daniel, Barghouth, Paul G., Oviedo, Néstor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827215/
https://www.ncbi.nlm.nih.gov/pubmed/27068018
http://dx.doi.org/10.1186/s12861-016-0107-z