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8-Hydroxy-2-Deoxyguanosine Levels and Cardiovascular Disease: A Systematic Review and Meta-Analysis of the Literature

Significance: 8-Hydroxy-2-deoxyguanosine (8-OHdG) is generated after the repair of ROS-mediated DNA damages and, thus, is one of the most widely recognized biomarkers of oxidative damage of DNA because guanosine is the most oxidized among the DNA nucleobases. In several pathological conditions, high...

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Detalles Bibliográficos
Autores principales: Di Minno, Alessandro, Turnu, Linda, Porro, Benedetta, Squellerio, Isabella, Cavalca, Viviana, Tremoli, Elena, Di Minno, Matteo Nicola Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827317/
https://www.ncbi.nlm.nih.gov/pubmed/26650622
http://dx.doi.org/10.1089/ars.2015.6508