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Recombinant Human Elastase Alters the Compliance of Atherosclerotic Tibial Arteries After Ex Vivo Angioplasty

PURPOSE: This study was designed to determine whether vonapanitase (formerly PRT-201), a recombinant human elastase, treatment can fragment the protein elastin in elastic fibers and cause dilation of atherosclerotic human peripheral arteries subjected to ex vivo balloon angioplasty. MATERIALS AND ME...

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Detalles Bibliográficos
Autores principales: Burke, Steven K., Bingham, Karen, Moss, Emma, Gottlieb, Daniel P., Wong, Marco D., Bland, Kimberly S., Franano, F. Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827324/
https://www.ncbi.nlm.nih.gov/pubmed/26745001
http://dx.doi.org/10.1097/FJC.0000000000000354