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Intratracheal Administration of Prostacyclin Analogue–incorporated Nanoparticles Ameliorates the Development of Monocrotaline and Sugen-Hypoxia-induced Pulmonary Arterial Hypertension

Nanoparticles (NPs) have been used as novel drug delivery systems. Drug-incorporated NPs for local delivery might optimize the efficacy and minimize the side effects of drugs. Intravenous prostacyclin improves long-term survival in patients with pulmonary arterial hypertension (PAH), but it causes s...

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Detalles Bibliográficos
Autores principales: Akagi, Satoshi, Nakamura, Kazufumi, Matsubara, Hiromi, Kondo, Megumi, Miura, Daiji, Matoba, Tetsuya, Egashira, Kensuke, Ito, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827325/
https://www.ncbi.nlm.nih.gov/pubmed/26745002
http://dx.doi.org/10.1097/FJC.0000000000000352