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Intratracheal Administration of Prostacyclin Analogue–incorporated Nanoparticles Ameliorates the Development of Monocrotaline and Sugen-Hypoxia-induced Pulmonary Arterial Hypertension
Nanoparticles (NPs) have been used as novel drug delivery systems. Drug-incorporated NPs for local delivery might optimize the efficacy and minimize the side effects of drugs. Intravenous prostacyclin improves long-term survival in patients with pulmonary arterial hypertension (PAH), but it causes s...
Autores principales: | Akagi, Satoshi, Nakamura, Kazufumi, Matsubara, Hiromi, Kondo, Megumi, Miura, Daiji, Matoba, Tetsuya, Egashira, Kensuke, Ito, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Cardiovascular Pharmacology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827325/ https://www.ncbi.nlm.nih.gov/pubmed/26745002 http://dx.doi.org/10.1097/FJC.0000000000000352 |
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