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Investigating how the attributes of self-associated drug complexes influence the passive transport of molecules through biological membranes

Relatively little is known about how drug self-association influences absorption into the human body. This study presented two hydrophobic membranes with a series of solutions containing different types of tetracaine aggregates with the aim of understanding how the attributes of supramolecular aggre...

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Detalles Bibliográficos
Autores principales: Inacio, R., Barlow, D., Kong, X., Keeble, J., Jones, S.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827376/
https://www.ncbi.nlm.nih.gov/pubmed/26965142
http://dx.doi.org/10.1016/j.ejpb.2016.03.002