Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand

[Image: see text] The covalent attachment of synthetic photoswitches is a general approach to impart light sensitivity onto native receptors. It mimics the logic of natural photoreceptors and significantly expands the reach of optogenetics. Here we describe a novel photoswitch design—the photoswitch...

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Detalles Bibliográficos
Autores principales: Broichhagen, Johannes, Damijonaitis, Arunas, Levitz, Joshua, Sokol, Kevin R., Leippe, Philipp, Konrad, David, Isacoff, Ehud Y., Trauner, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827557/
https://www.ncbi.nlm.nih.gov/pubmed/27162996
http://dx.doi.org/10.1021/acscentsci.5b00260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827557/
https://www.ncbi.nlm.nih.gov/pubmed/27162996
http://dx.doi.org/10.1021/acscentsci.5b00260

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