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New distinct compartments in the G(2) phase of the cell cycle defined by the levels of γH2AX.

Induction of DNA double strand breaks leads to phosphorylation and focus-formation of H2AX. However, foci of phosphorylated H2AX (γH2AX) appear during DNA replication also in the absence of exogenously applied injury. We measured the amount and the number of foci of γH2AX in different phases of the...

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Detalles Bibliográficos
Autores principales: Dale Rein, Idun, Stokke, Caroline, Jalal, Marwa, Myklebust, June H, Patzke, Sebastian, Stokke, Trond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827887/
https://www.ncbi.nlm.nih.gov/pubmed/26317799
http://dx.doi.org/10.1080/15384101.2015.1087617