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Downregulation of microRNA-122 promotes proliferation, migration, and invasion of human hepatocellular carcinoma cells by activating epithelial–mesenchymal transition

OBJECTIVE: To investigate the effects of microRNA-122 (miR-122) on proliferation, migration, and invasion in human hepatocellular carcinoma (HCC) cells by activating epithelial–mesenchymal transition (EMT) pathways. METHODS: miR-122 mimics, miR-122 inhibitors, relevant control oligonucleotides, and...

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Detalles Bibliográficos
Autores principales: Wang, Nanyao, Wang, Qiong, Shen, Dong, Sun, Xia, Cao, Xiangming, Wu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827919/
https://www.ncbi.nlm.nih.gov/pubmed/27103830
http://dx.doi.org/10.2147/OTT.S92378