Novel in situ self-assembly nanoparticles for formulating a poorly water-soluble drug in oral solid granules, improving stability, palatability, and bioavailability

PURPOSE: The purpose of this study was to develop a novel lipid-based nanotechnology to formulate poorly water-soluble drugs in oral solid granules to improve stability, palatability, and bioavailability. MATERIALS AND METHODS: In one method, we prepared ritonavir (RTV) nanoparticles (NPs) by a micr...

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Detalles Bibliográficos
Autores principales: Guo, Shujie, Pham, Kevin, Li, Diana, Penzak, Scott R, Dong, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827924/
https://www.ncbi.nlm.nih.gov/pubmed/27103803
http://dx.doi.org/10.2147/IJN.S100621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827924/
https://www.ncbi.nlm.nih.gov/pubmed/27103803
http://dx.doi.org/10.2147/IJN.S100621

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