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Electrocardiographic Characterization of Ramucirumab on the Corrected QT Interval in a Phase II Study of Patients With Advanced Solid Tumors

LESSONS LEARNED: Cardiotoxicity can be a serious complication of anticancer therapies. To enable earlier identification of drug-related cardiac effects, the International Conference on Harmonization (ICH) adopted the ICH E14 Guidelines for evaluating the potential for QT/corrected QT (QTc) interval...

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Detalles Bibliográficos
Autores principales: Olszanski, Anthony J., Smith, David C., Camacho, Luis H., Thompson, John, Ramalingam, Suresh S., Harvey, R. Donald, Campos, Luis, Ferry, David, Tang, Shande, Gao, Ling, Safran, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828123/
https://www.ncbi.nlm.nih.gov/pubmed/26984445
http://dx.doi.org/10.1634/theoncologist.2015-0467