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Production of Double-stranded DNA Ministrings

We constructed linear covalently closed (LCC) DNA minivectors as a non-viral gene-delivery vector alternative produced via a simple platform in vivo. DNA ministrings possess a heightened safety profile and also efficiently deliver DNA cargo to targeted cells. Conventional DNA vectors carry undesirab...

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Detalles Bibliográficos
Autores principales: Wong, Shirley, Lam, Peggy, Nafissi, Nafiseh, Denniss, Steven, Slavcev, Roderick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828204/
https://www.ncbi.nlm.nih.gov/pubmed/26967586
http://dx.doi.org/10.3791/53177