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Central antinociceptive activity of peripherally applied botulinum toxin type A in lab rat model of trigeminal neuralgia

BACKGROUND: BoNT-A is often used in the clinical treatment for movement disorders. In recent years, various clinical studies suggest that BoNT-A can effectively alleviate pain caused by trigeminal neuralgia (TN); however, its mechanism remains unclear. METHODS: In this study, we used a lab rat model...

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Detalles Bibliográficos
Autores principales: Wu, Chuanjie, Xie, Nanchang, Lian, Yajun, Xu, Hongliang, Chen, Chen, Zheng, Yake, Chen, Yuan, Zhang, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828356/
https://www.ncbi.nlm.nih.gov/pubmed/27104119
http://dx.doi.org/10.1186/s40064-016-2071-2