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Central antinociceptive activity of peripherally applied botulinum toxin type A in lab rat model of trigeminal neuralgia
BACKGROUND: BoNT-A is often used in the clinical treatment for movement disorders. In recent years, various clinical studies suggest that BoNT-A can effectively alleviate pain caused by trigeminal neuralgia (TN); however, its mechanism remains unclear. METHODS: In this study, we used a lab rat model...
Autores principales: | Wu, Chuanjie, Xie, Nanchang, Lian, Yajun, Xu, Hongliang, Chen, Chen, Zheng, Yake, Chen, Yuan, Zhang, Haifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828356/ https://www.ncbi.nlm.nih.gov/pubmed/27104119 http://dx.doi.org/10.1186/s40064-016-2071-2 |
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