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Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity

Diet and microbiome derived indole derivatives are known to activate the ligand induced transcription factor, the Aryl hydrocarbon Receptor (AhR). While the current understanding of AhR biology has confirmed its role in mucosal lymphocytes, its function in intestinal antigen presenting cells (APCs)...

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Detalles Bibliográficos
Autores principales: Chng, Song Hui, Kundu, Parag, Dominguez-Brauer, Carmen, Teo, Wei Ling, Kawajiri, Kaname, Fujii-Kuriyama, Yoshiaki, Mak, Tak Wah, Pettersson, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828637/
https://www.ncbi.nlm.nih.gov/pubmed/27068235
http://dx.doi.org/10.1038/srep23820