RUNX2 Mutation Impairs 1α,25-Dihydroxyvitamin D(3) mediated Osteoclastogenesis in Dental Follicle Cells

Cleidocranial dysplasia (CCD), a skeletal disorder characterized by delayed permanent tooth eruption and other dental abnormalities, is caused by heterozygous RUNX2 mutations. As an osteoblast-specific transcription factor, RUNX2 plays a role in bone remodeling, tooth formation and tooth eruption. T...

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Detalles Bibliográficos
Autores principales: Wang, X. Z., Sun, X. Y., Zhang, C. Y., Yang, X., Yan, W. J., Ge, L. H., Zheng, S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828645/
https://www.ncbi.nlm.nih.gov/pubmed/27068678
http://dx.doi.org/10.1038/srep24225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828645/
https://www.ncbi.nlm.nih.gov/pubmed/27068678
http://dx.doi.org/10.1038/srep24225

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