Genome-wide CRISPR screen reveals novel host factors required for Staphylococcus aureus α-hemolysin-mediated toxicity

Staphylococcus aureus causes a wide variety of infections and antibiotic resistant strains are a major problem in hospitals. One of the best studied virulence factors of S. aureus is the pore-forming toxin alpha hemolysin (αHL) whose mechanism of action is incompletely understood. We performed a gen...

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Detalles Bibliográficos
Autores principales: Virreira Winter, Sebastian, Zychlinsky, Arturo, Bardoel, Bart W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828653/
https://www.ncbi.nlm.nih.gov/pubmed/27066838
http://dx.doi.org/10.1038/srep24242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828653/
https://www.ncbi.nlm.nih.gov/pubmed/27066838
http://dx.doi.org/10.1038/srep24242

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