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Genome-wide CRISPR screen reveals novel host factors required for Staphylococcus aureus α-hemolysin-mediated toxicity

Staphylococcus aureus causes a wide variety of infections and antibiotic resistant strains are a major problem in hospitals. One of the best studied virulence factors of S. aureus is the pore-forming toxin alpha hemolysin (αHL) whose mechanism of action is incompletely understood. We performed a gen...

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Detalles Bibliográficos
Autores principales:	Virreira Winter, Sebastian, Zychlinsky, Arturo, Bardoel, Bart W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828653/ https://www.ncbi.nlm.nih.gov/pubmed/27066838 http://dx.doi.org/10.1038/srep24242

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