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CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice

CALHM1 is a cell surface calcium channel expressed in cerebral neurons. CALHM1 function in the brain remains unknown, but recent results showed that neuronal CALHM1 controls intracellular calcium signaling and cell excitability, two mechanisms required for synaptic function. Here, we describe the ge...

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Detalles Bibliográficos
Autores principales: Vingtdeux, Valérie, Chang, Eric H., Frattini, Stephen A., Zhao, Haitian, Chandakkar, Pallavi, Adrien, Leslie, Strohl, Joshua J., Gibson, Elizabeth L., Ohmoto, Makoto, Matsumoto, Ichiro, Huerta, Patricio T., Marambaud, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828655/
https://www.ncbi.nlm.nih.gov/pubmed/27066908
http://dx.doi.org/10.1038/srep24250