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C/EBPβ-Thr217 Phosphorylation Stimulates Macrophage Inflammasome Activation and Liver Injury

Amplification of liver injury is mediated by macrophages but the signaling by which the macrophage inflammasome enhances liver injury is not completely understood. The CCAAT/Enhancer Binding Protein-β (C/EBPβ) is a critical signaling molecule for macrophages because expression of a dominant inhibito...

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Detalles Bibliográficos
Autores principales: Buck, Martina, Solis-Herruzo, Jose, Chojkier, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828658/
https://www.ncbi.nlm.nih.gov/pubmed/27067260
http://dx.doi.org/10.1038/srep24268