Doa1 targets ubiquitinated substrates for mitochondria-associated degradation

Mitochondria-associated degradation (MAD) mediated by the Cdc48 complex and proteasome degrades ubiquitinated mitochondrial outer-membrane proteins. MAD is critical for mitochondrial proteostasis, but it remains poorly characterized. We identified several mitochondrial Cdc48 substrates and developed...

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Detalles Bibliográficos
Autores principales: Wu, Xi, Li, Lanlan, Jiang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828692/
https://www.ncbi.nlm.nih.gov/pubmed/27044889
http://dx.doi.org/10.1083/jcb.201510098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828692/
https://www.ncbi.nlm.nih.gov/pubmed/27044889
http://dx.doi.org/10.1083/jcb.201510098

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