Monocyte-derived macrophages exhibit distinct and more restricted HIV-1 integration site repertoire than CD4(+) T cells

The host genetic landscape surrounding integrated HIV-1 has an impact on the fate of the provirus. Studies analysing HIV-1 integration sites in macrophages are scarce. We studied HIV-1 integration site patterns in monocyte-derived macrophages (MDMs) and activated CD4(+) T cells derived from seven an...

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Detalles Bibliográficos
Autores principales: Kok, Yik Lim, Vongrad, Valentina, Shilaih, Mohaned, Di Giallonardo, Francesca, Kuster, Herbert, Kouyos, Roger, Günthard, Huldrych F., Metzner, Karin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828718/
https://www.ncbi.nlm.nih.gov/pubmed/27067385
http://dx.doi.org/10.1038/srep24157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828718/
https://www.ncbi.nlm.nih.gov/pubmed/27067385
http://dx.doi.org/10.1038/srep24157

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