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Overexpression of the Replicative Helicase in Escherichia coli Inhibits Replication Initiation and Replication Fork Reloading

Replicative helicases play central roles in chromosome duplication and their assembly onto DNA is regulated via initiators and helicase loader proteins. The Escherichia coli replicative helicase DnaB and the helicase loader DnaC form a DnaB(6)–DnaC(6) complex that is required for loading DnaB onto s...

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Detalles Bibliográficos
Autores principales: Brüning, Jan-Gert, Myka, Kamila Katarzyna, McGlynn, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828956/
https://www.ncbi.nlm.nih.gov/pubmed/26812209
http://dx.doi.org/10.1016/j.jmb.2016.01.018