Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

Allopurinol and its active metabolite, oxypurinol are widely used in the treatment of gout and hyperuricemia. They inhibit xanthine oxidase (XO) an enzyme in the purine degradation pathway that converts xanthine to uric acid. This investigation examined the effect of allopurinol and oxypurinol on bo...

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Detalles Bibliográficos
Autores principales: Orriss, Isabel R., Arnett, Timothy R., George, Jacob, Witham, Miles D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829071/
https://www.ncbi.nlm.nih.gov/pubmed/26968635
http://dx.doi.org/10.1016/j.yexcr.2016.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829071/
https://www.ncbi.nlm.nih.gov/pubmed/26968635
http://dx.doi.org/10.1016/j.yexcr.2016.03.004

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