ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure

PURPOSE: Sulfur mustard, nitrogen mustard (NM), and 2-chloroethyl ethyl sulfide all cause corneal injury with epithelial–stromal separation, differing only by degree. Injury can resolve in a few weeks or develop into chronic corneal problems. These vesicants induce microbullae at the epithelial–stro...

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Detalles Bibliográficos
Autores principales: DeSantis-Rodrigues, Andrea, Chang, Yoke-Chen, A. Hahn, Rita, P. Po, Iris, Zhou, Peihong, Lacey, C. Jeffrey, Pillai, Abhilash, C. Young, Sherri, A. Flowers II, Robert, A. Gallo, Michael, D. Laskin, Jeffrey, R. Gerecke, Donald, K. H. Svoboda, Kathy, D. Heindel, Ned, Gordon, Marion K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829087/
https://www.ncbi.nlm.nih.gov/pubmed/27058125
http://dx.doi.org/10.1167/iovs.15-17269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829087/
https://www.ncbi.nlm.nih.gov/pubmed/27058125
http://dx.doi.org/10.1167/iovs.15-17269

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