Cargando…

ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure

PURPOSE: Sulfur mustard, nitrogen mustard (NM), and 2-chloroethyl ethyl sulfide all cause corneal injury with epithelial–stromal separation, differing only by degree. Injury can resolve in a few weeks or develop into chronic corneal problems. These vesicants induce microbullae at the epithelial–stro...

Descripción completa

Detalles Bibliográficos
Autores principales:	DeSantis-Rodrigues, Andrea, Chang, Yoke-Chen, A. Hahn, Rita, P. Po, Iris, Zhou, Peihong, Lacey, C. Jeffrey, Pillai, Abhilash, C. Young, Sherri, A. Flowers II, Robert, A. Gallo, Michael, D. Laskin, Jeffrey, R. Gerecke, Donald, K. H. Svoboda, Kathy, D. Heindel, Ned, Gordon, Marion K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2016
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829087/ https://www.ncbi.nlm.nih.gov/pubmed/27058125 http://dx.doi.org/10.1167/iovs.15-17269

Ejemplares similares

An Engineered Human Fibroblast Growth Factor-1 Derivative, TTHX1114, Ameliorates Short-term Corneal Nitrogen Mustard Injury in Rabbit Organ Cultures
por: Eveleth, David D., et al.
Publicado: (2018)

EphA2/Ephrin-A1 Mediate Corneal Epithelial Cell Compartmentalization via ADAM10 Regulation of EGFR Signaling
por: Kaplan, Nihal, et al.
Publicado: (2018)

Novel Identity and Functional Markers for Human Corneal Endothelial Cells
por: Bartakova, Alena, et al.
Publicado: (2016)

A Cell Culture Approach to Optimized Human Corneal Endothelial Cell Function
por: Bartakova, Alena, et al.
Publicado: (2018)

Role of the Phospholipase C Pathway and Calcium Mobilization in Oxytocin-Induced Contraction of Lacrimal Gland Myoepithelial Cells
por: Gárriz, Angela, et al.
Publicado: (2021)

Magnetic Human Corneal Endothelial Cell Transplant: Delivery, Retention, and Short-Term Efficacy
por: Xia, Xin, et al.
Publicado: (2019)

Influence of Vitamin D on Corneal Epithelial Cell Desmosomes and Hemidesmosomes
por: Lu, Xiaowen, et al.
Publicado: (2019)

Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium
por: Choi, Moonjung, et al.
Publicado: (2021)

Generation of Human Corneal Endothelial Cells via In Vitro Ocular Lineage Restriction of Pluripotent Stem Cells
por: Zhao, Jiagang J., et al.
Publicado: (2016)

Disease Expression and Familial Transmission of Fuchs Endothelial Corneal Dystrophy With and Without CTG18.1 Expansion
por: Xu, Timothy T., et al.
Publicado: (2021)

Cyclic Change of Fatty Acid Composition in Meibum During the Menstrual Cycle
por: Suzuki, Tomo, et al.
Publicado: (2019)

Myh11 Lineage Corneal Endothelial Cells and ASCs Populate Corneal Endothelium
por: Corliss, Bruce A., et al.
Publicado: (2019)

Do Cyclosporine A, an IL-1 Receptor Antagonist, Uridine Triphosphate, Rebamipide, and/or Bimatoprost Regulate Human Meibomian Gland Epithelial Cells?
por: Kam, Wendy R., et al.
Publicado: (2016)

Corneal Endothelial Pump Coupling to Lactic Acid Efflux in the Rabbit and Mouse
por: Li, Shimin, et al.
Publicado: (2020)

Diurnal Control of Sensory Axon Growth and Shedding in the Mouse Cornea
por: Pal-Ghosh, Sonali, et al.
Publicado: (2020)

DMEK after penetrating keratoplasty: cohort with DMEK grafts and descemetorhexis larger than full-thickness graft
por: Steindor, F. A., et al.
Publicado: (2022)

Association of Ocular Surface Immune Cells With Dry Eye Signs and Symptoms in the Dry Eye Assessment and Management (DREAM) Study
por: Kuklinski, Eric J., et al.
Publicado: (2023)

Corneal Stroma Cell Density Evolution in Keratoconus Corneas Following the Implantation of Adipose Mesenchymal Stem Cells and Corneal Laminas: An In Vivo Confocal Microscopy Study
por: El Zarif, Mona, et al.
Publicado: (2020)

Type II Diabetes Mellitus Causes Extracellular Matrix Alterations in the Posterior Cornea That Increase Graft Thickness and Rigidity
por: Kingsbury, Kenten D., et al.
Publicado: (2023)

The Role of Hypoxia-Inducible Factor 1α in the Regulation of Human Meibomian Gland Epithelial Cells
por: Liu, Yang, et al.
Publicado: (2020)

Quasi-Static Optical Coherence Elastography to Characterize Human Corneal Biomechanical Properties
por: Kling, Sabine, et al.
Publicado: (2020)

Morphological characterization and clinical effects of stromal alterations after intracorneal ring segment implantation in keratoconus
por: Hamon, Loïc, et al.
Publicado: (2022)

Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1-Null Mice: Implications to Meibomian Gland Dysfunction and Dry Eye Disease
por: Xu, Xiaojie, et al.
Publicado: (2023)

CTG18.1 Expansion in TCF4 Among African Americans With Fuchs' Corneal Dystrophy
por: Eghrari, Allen O., et al.
Publicado: (2017)

Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea
por: Díaz, Nicolás M., et al.
Publicado: (2020)

Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy
por: Shyam, Rajalekshmy, et al.
Publicado: (2021)

Graft survival of Descemet membrane endothelial keratoplasty (DMEK) in corneal endothelial decompensation after glaucoma surgery
por: Schrittenlocher, Silvia, et al.
Publicado: (2021)

Inhibition of Human Corneal Myofibroblast Formation
por: Guo, Xiaoqing, et al.
Publicado: (2018)

Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways
por: Lippestad, Marit, et al.
Publicado: (2017)

Association of Tear Osmolarity With Signs and Symptoms of Dry Eye Disease in the Dry Eye Assessment and Management (DREAM) Study
por: Greiner, Jack V., et al.
Publicado: (2023)

Activation of the EGF Receptor by Histamine Receptor Subtypes Stimulates Mucin Secretion in Conjunctival Goblet Cells
por: He, Min, et al.
Publicado: (2018)

Corneal Collagen Ordering After In Vivo Rose Bengal and Riboflavin Cross-Linking
por: Germann, James A., et al.
Publicado: (2020)

Labial Mucosa Stem Cells: Isolation, Characterization, and Their Potential for Corneal Epithelial Reconstruction
por: Zhurenkov, Kirill E., et al.
Publicado: (2022)

Individualized Characterization of the Distribution of Collagen Fibril Dispersion Using Optical Aberrations of the Cornea for Biomechanical Models
por: Xu, Mengchen, et al.
Publicado: (2020)

Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump
por: Ogando, Diego G., et al.
Publicado: (2021)

Screening and Characterization of Drugs That Protect Corneal Endothelial Cells Against Unfolded Protein Response and Oxidative Stress
por: Kim, Eun Chul, et al.
Publicado: (2017)

Corneal Endothelial Cell Migration and Proliferation Enhanced by Rho Kinase (ROCK) Inhibitors in In Vitro and In Vivo Models
por: Meekins, Landon C., et al.
Publicado: (2016)

An Investigation of the Effects of Riboflavin Concentration on the Efficacy of Corneal Cross-Linking Using an Enzymatic Resistance Model in Porcine Corneas
por: O'Brart, Naomi A. L., et al.
Publicado: (2019)

Dysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide
por: Wang, Changjun, et al.
Publicado: (2019)

PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts
por: Sriram, Sriniwas, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pfrkcesvv2q4cd8a7stbqa41ec