A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury

PURPOSE: Morphologic and genetic evidence exists that an overactive complement system driven by the complement alternative pathway (AP) is involved in pathogenesis of age-related macular degeneration (AMD). Smoking is the only modifiable risk factor for AMD. As we have shown that smoke-related ocula...

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Detalles Bibliográficos
Autores principales: Woodell, Alex, Jones, Bryan W., Williamson, Tucker, Schnabolk, Gloriane, Tomlinson, Stephen, Atkinson, Carl, Rohrer, Bärbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829088/
https://www.ncbi.nlm.nih.gov/pubmed/27064393
http://dx.doi.org/10.1167/iovs.15-18471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829088/
https://www.ncbi.nlm.nih.gov/pubmed/27064393
http://dx.doi.org/10.1167/iovs.15-18471

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