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A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury
PURPOSE: Morphologic and genetic evidence exists that an overactive complement system driven by the complement alternative pathway (AP) is involved in pathogenesis of age-related macular degeneration (AMD). Smoking is the only modifiable risk factor for AMD. As we have shown that smoke-related ocula...
Autores principales: | Woodell, Alex, Jones, Bryan W., Williamson, Tucker, Schnabolk, Gloriane, Tomlinson, Stephen, Atkinson, Carl, Rohrer, Bärbel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829088/ https://www.ncbi.nlm.nih.gov/pubmed/27064393 http://dx.doi.org/10.1167/iovs.15-18471 |
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