Cargando…
Absence of Peroxiredoxin 6 Amplifies the Effect of Oxidant Stress on Mobility and SCSA/CMA3 Defined Chromatin Quality and Impairs Fertilizing Ability of Mouse Spermatozoa
Oxidative stress, the imbalance between reactive oxygen species production and antioxidant defenses, is associated with male infertility. Peroxiredoxins (PRDXs) are antioxidant enzymes with a wide distribution in spermatozoa. PRDX6 is highly abundant and located in all subcellular compartments of th...
Autores principales: | Ozkosem, Burak, Feinstein, Sheldon I., Fisher, Aron B., O'Flaherty, Cristian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for the Study of Reproduction, Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829091/ https://www.ncbi.nlm.nih.gov/pubmed/26792942 http://dx.doi.org/10.1095/biolreprod.115.137646 |
Ejemplares similares
-
Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice
por: Ozkosem, Burak, et al.
Publicado: (2015) -
Peroxiredoxins: hidden players in the antioxidant defence of human spermatozoa
por: O’Flaherty, Cristian
Publicado: (2014) -
Peroxiredoxin 6: The Protector of Male Fertility
por: O’Flaherty, Cristian
Publicado: (2018) -
Deficiency of peroxiredoxin 6 or inhibition of its phospholipase A(2) activity impair the in vitro sperm fertilizing competence in mice
por: Moawad, Adel R., et al.
Publicado: (2017) -
Peroxiredoxin 6 Peroxidase and Ca(2+)-Independent Phospholipase A(2) Activities Are Essential to Support Male-Mouse Fertility
por: Bumanlag, Edrian, et al.
Publicado: (2022)