PI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1

Activation of T lymphocytes by peptide/major histocompatibility complex on antigen-presenting cells (APCs) involves dynamic contacts between the two cells, during which T cells undergo marked morphological changes. These interactions are facilitated by integrins. Activation of the T cells increases...

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Detalles Bibliográficos
Autores principales: Garçon, Fabien, Okkenhaug, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829101/
https://www.ncbi.nlm.nih.gov/pubmed/26740009
http://dx.doi.org/10.1038/icb.2016.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829101/
https://www.ncbi.nlm.nih.gov/pubmed/26740009
http://dx.doi.org/10.1038/icb.2016.1

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