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A novel uPAg-KPI fusion protein inhibits the growth and invasion of human ovarian cancer cells in vitro
Urokinase-type plasminogen activator (uPA) acts by breaking down the basement membrane and is involved in cell proliferation, migration and invasion. These actions are mediated by binding to the uPA receptor (uPAR) via its growth factor domain (GFD). The present study evaluated the effects of uPAg-K...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829131/ https://www.ncbi.nlm.nih.gov/pubmed/27035617 http://dx.doi.org/10.3892/ijmm.2016.2540 |