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A novel uPAg-KPI fusion protein inhibits the growth and invasion of human ovarian cancer cells in vitro

Urokinase-type plasminogen activator (uPA) acts by breaking down the basement membrane and is involved in cell proliferation, migration and invasion. These actions are mediated by binding to the uPA receptor (uPAR) via its growth factor domain (GFD). The present study evaluated the effects of uPAg-K...

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Detalles Bibliográficos
Autores principales: ZHAO, LI-PING, XU, TIAN-MIN, KAN, MU-JIE, XIAO, YE-CHEN, CUI, MAN-HUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829131/
https://www.ncbi.nlm.nih.gov/pubmed/27035617
http://dx.doi.org/10.3892/ijmm.2016.2540