High-mobility group box 1 impairs airway epithelial barrier function through the activation of the RAGE/ERK pathway

Recent studies have indicated that high-mobility group box 1 protein (HMGB1) and the receptor for advanced glycation end-products (RAGE) contribute to the pathogenesis of asthma. However, whether the activation of the HMGB1/RAGE axis mediates airway epithelial barrier dysfunction remains unknown. Th...

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Detalles Bibliográficos
Autores principales: HUANG, WUFENG, ZHAO, HAIJIN, DONG, HANGMING, WU, YUE, YAO, LIHONG, ZOU, FEI, CAI, SHAOXI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829140/
https://www.ncbi.nlm.nih.gov/pubmed/27035254
http://dx.doi.org/10.3892/ijmm.2016.2537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829140/
https://www.ncbi.nlm.nih.gov/pubmed/27035254
http://dx.doi.org/10.3892/ijmm.2016.2537

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