Celastrol attenuates oxidative stress in the skeletal muscle of diabetic rats by regulating the AMPK-PGC1α-SIRT3 signaling pathway

Oxidative stress plays a key role in the pathogenesis of diabetic myopathy. Celastrol provides a wide range of health benefits, including antioxidant, anti-inflammatory and antitumor effects. We hypothesized that celastrol may exert an antioxidant effect in the skeletal muscle of diabetic rats. In t...

Descripción completa

Detalles Bibliográficos
Autores principales: GUAN, YUE, CUI, ZI-JIAN, SUN, BEI, HAN, LI-PING, LI, CHUN-JUN, CHEN, LI-MING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829141/
https://www.ncbi.nlm.nih.gov/pubmed/27049825
http://dx.doi.org/10.3892/ijmm.2016.2549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829141/
https://www.ncbi.nlm.nih.gov/pubmed/27049825
http://dx.doi.org/10.3892/ijmm.2016.2549

Ejemplares similares