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Celastrol attenuates oxidative stress in the skeletal muscle of diabetic rats by regulating the AMPK-PGC1α-SIRT3 signaling pathway

Oxidative stress plays a key role in the pathogenesis of diabetic myopathy. Celastrol provides a wide range of health benefits, including antioxidant, anti-inflammatory and antitumor effects. We hypothesized that celastrol may exert an antioxidant effect in the skeletal muscle of diabetic rats. In t...

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Detalles Bibliográficos
Autores principales:	GUAN, YUE, CUI, ZI-JIAN, SUN, BEI, HAN, LI-PING, LI, CHUN-JUN, CHEN, LI-MING
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829141/ https://www.ncbi.nlm.nih.gov/pubmed/27049825 http://dx.doi.org/10.3892/ijmm.2016.2549

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