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Celastrol attenuates oxidative stress in the skeletal muscle of diabetic rats by regulating the AMPK-PGC1α-SIRT3 signaling pathway
Oxidative stress plays a key role in the pathogenesis of diabetic myopathy. Celastrol provides a wide range of health benefits, including antioxidant, anti-inflammatory and antitumor effects. We hypothesized that celastrol may exert an antioxidant effect in the skeletal muscle of diabetic rats. In t...
Главные авторы: | , , , , , |
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Формат: | Online Статья Текст |
Язык: | English |
Опубликовано: |
D.A. Spandidos
2016
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Предметы: | |
Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829141/ https://www.ncbi.nlm.nih.gov/pubmed/27049825 http://dx.doi.org/10.3892/ijmm.2016.2549 |