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Magnobovatol inhibits smooth muscle cell migration by suppressing PDGF-Rβ phosphorylation and inhibiting matrix metalloproteinase-2 expression

The migration of vascular smooth muscle cells (VSMCs) may play a crucial role in the pathogenesis of vascular diseases, such as atherosclerosis and post-angioplasty restenosis. Platelet-derived growth factor (PDGF)-BB is a potent mitogen for VSMCs and plays an important role in the intimal accumulat...

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Detalles Bibliográficos
Autores principales: KANG, HYREEN, AHN, DONG HYEON, PAK, JHANG HO, SEO, KYEONG-HWA, BAEK, NAM-IN, JANG, SUNG-WUK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829143/
https://www.ncbi.nlm.nih.gov/pubmed/27049716
http://dx.doi.org/10.3892/ijmm.2016.2548