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Magnobovatol inhibits smooth muscle cell migration by suppressing PDGF-Rβ phosphorylation and inhibiting matrix metalloproteinase-2 expression
The migration of vascular smooth muscle cells (VSMCs) may play a crucial role in the pathogenesis of vascular diseases, such as atherosclerosis and post-angioplasty restenosis. Platelet-derived growth factor (PDGF)-BB is a potent mitogen for VSMCs and plays an important role in the intimal accumulat...
Autores principales: | KANG, HYREEN, AHN, DONG HYEON, PAK, JHANG HO, SEO, KYEONG-HWA, BAEK, NAM-IN, JANG, SUNG-WUK |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829143/ https://www.ncbi.nlm.nih.gov/pubmed/27049716 http://dx.doi.org/10.3892/ijmm.2016.2548 |
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